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The search for a gene involved in the determination of limited duplicative capacity in human cells

โœ Scribed by E. Calef; A. Scotto d'Abusco; E. Bianchi; S. Gargano; A. Fruscalzo


Book ID
105200437
Publisher
Springer Netherlands
Year
1994
Tongue
English
Weight
415 KB
Volume
94
Category
Article
ISSN
0016-6707

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## Abstract Mature B cells, upon activation, progressively differentiate through centroblasts into centrocytes and finally to plasmacytes that express large amounts of selected immunoglobulins. A significant part of this maturation is thought to involve induction of the unfolded protein response (U