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Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells

✍ Scribed by van Agthoven, T.


Book ID
111745421
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
748 KB
Volume
17
Category
Article
ISSN
0261-4189

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Development of anti-estrogen resistance limits the benefit of endocrine therapy of breast cancer. The mechanistic basis for resistance to the anti-estrogen tamoxifen may involve (epi)genetic alterations within tumor cells. We have initiated a random search for genes allowing estrogen-dependent ZR-75