✦ LIBER ✦

The safety of risperidone: a post-marketing study on 7684 patients

✍ Scribed by F. J. Mackay; L. V. Wilton; G. L. Pearce; S. N. Freemantle; R. D. Mann

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 91 KB
Volume: 13
Category: Article
ISSN: 0885-6222
DOI: 10.1002/(sici)1099-1077(199808)13:6<413::aid-hup12>3.0.co;2-a

No coin nor oath required. For personal study only.

✦ Synopsis

Risperidone is a relatively new antipsychotic agent licensed for the treatment of schizophrenia and other psychotic conditions in patients aged 15 years or older. This study examines the safety of risperidone used in general practice. Information was collected for 7684 patients included in a non-interventional observational cohort study conducted by means of Prescription-Event Monitoring. Incidence rates were calculated to rank the frequency of reported events. Drowsiness/sedation was the most frequent reason for stopping risperidone and the most frequently reported event. Extrapyramidal symptoms were reported rarely, but were more frequent in the elderly. 98 (1 . 3 per cent) patients were aged less than 15 years. Eight overdoses of risperidone alone were reported with no serious clinical sequelae. Risperidone appears to be well tolerated.

📜 SIMILAR VOLUMES

A comparison of the efficacy and safety

A comparison of the efficacy and safety of olanzapine and risperidone in the treatment of elderly patients with schizophrenia: an open study of six months duration

✍ C. W. Ritchie; E. Chiu; S. Harrigan; S. Macfarlane; M. Mastwyk; G. Halliday; H. 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 117 KB 👁 3 views

Background Following an earlier study in which elderly patients with schizophrenia had their typical antipsychotic medication changed to olanzapine or risperidone, the 61 patients were followed for up to a further six months to see if either treatment was superior in terms of efficacy or side effect

A pilot, open study on the treatment of

A pilot, open study on the treatment of refractory schizophrenia with risperidone and clozapine

✍ Roberto Cavallaro; Cristina Colombo; Enrico Smeraldi 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 273 KB 👁 2 views

The aim of this report is to show the results of a pilot, open label treatment programme for resistant schizophrenia in which risperidone was used before clozapine. Thirteen DSM I11 R, drug resistant schizophrenics were treated with risperidone p.0. at doses up to 16 mg/day for three months. Clinica

A preliminary study of the comparative e

A preliminary study of the comparative effects of olanzapine and risperidone on cognition in schizophrenia

✍ Yang-Tae Kim; Byung-Jo Kang 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 59 KB 👁 2 views

## Abstract The aim of this study was to compare the effects of olanzapine and risperidone on cognitive functions in patients with schizophrenia. The subjects were schizophrenic outpatients, all meeting DSM‐IV diagnostic criteria for schizophrenia and already treated with risperidone. In the experi

Limitations in discerning the effects of

Limitations in discerning the effects of risperidone and its 9-hydroxy metabolite on prolactin levels in a small study of patients with schizophrenia

✍ Gahan J. Pandina; Carla M. Canuso; Eriene Youssef; Mary Kujawa; Ramy Mahmoud 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 55 KB 👁 2 views

The effects of music therapy on reducing

The effects of music therapy on reducing agitation in patients with Alzheimer's disease, a pre-post study

✍ Maryam Zare; Azizeh Afkham Ebrahimi; Behrooz Birashk 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 64 KB 👁 3 views

A Memory Clinic model set up to diagnose and treat Alzheimer's Disease early in the course of the illness delayed time to institutionalisation by a median of 9 months compared to controls. Treatment included pre and post diagnostic counselling, and psychosocial interventions.

A Comparative Study on the Constitutive

A Comparative Study on the Constitutive Properties of Marketed Pesticides

✍ Gefei Hao; Qingjian Dong; Guangfu Yang 📂 Article 📅 2011 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 375 KB

## Abstract The concept of drug‐likeness has been established in the field of drug discovery. Pesticide discovery is also a complicated and rigorous filtering process compared with drug discovery. This study involved investigation of the constitutive properties of 788 marketed pesticides, including