The physiological disposition offluvastatin, a potent inhibitor of hydroxymethylglutaryl-CoA reductase and thus cholesterol synthesis, has been studied in the mouse, rat, dog, and monkey using 14C-or 3H-labeled drug. Oral doses of fluvastatin were absorbed at a moderate to rapid rate. The extent of
✦ LIBER ✦
The Safety Evaluation of Fluvastatin, an HMG–CoA Reductase Inhibitor, in Beagle Dogs and Rhesus Monkeys
✍ Scribed by Howard A. Hartman; Laurie A. Myers; Morton Evans; Rodney L. Robison; Robert G. Engstrom; Francis L.S. Tse
- Book ID
- 115608557
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 148 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0272-0590
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