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Effect of the cholesterol absorption inhibitor SCH48461 in combination with the HMG-CoA reductase inhibitor lovastatin in rabbits, dogs and rhesus monkeys

โœ Scribed by H.R. Davis; R.W. Watkins; B.G. Salisbury; D.S. Compton; E.J. Sybertz; R.E. Burrier


Book ID
118325332
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
301 KB
Volume
109
Category
Article
ISSN
0021-9150

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Absorption and disposition of fluvastati
โœ F. L. S. Tse; D. Labbadia ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 464 KB ๐Ÿ‘ 2 views

The absorption and disposition of fluvastatin have been studied in the female rabbit. In naive rabbits receiving a single oral dose (1 mg kg-I) of [3H]fluvastatin, absorption was rapid and amounted to c. 90 per cent compared with an intravenous reference dose. The drug was subject to considerable fi