The safety and angiographic efficacy of tissue plasminogen activator in a cerebral embolization model
โ Scribed by David A. Phillips; Dr. Marc Fisher; Thomas W. Smith; Michael A. Davis
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 496 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
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The failure rate of replantations following a crush-avulsion type injury is high. This study has been designed to reproduce an effective standardized crush-avulsion injury model to the femoral artery of the rat and evaluate the antithrombotic efficacy of systemic intravenous administration of recomb
Tissue plasminogen activator (t-PA) is expressed by hypothalamic and peripheral sympathetic neurons. The sympathetic axons that permeate artery walls have not been investigated as possible sources of intramural t-PA. The plasmin produced by such a system would locally activate both fibrinolysis and