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The rotamase Pin1 is up-regulated, hypophosphorylated and required for cell cycle progression in head and neck squamous cell carcinomas

✍ Scribed by Susanne Wiegand; Branka Dakic; Ariane F.E. Rath; Galina Makarova; Carolina Sterz; Wolfgang Meissner; Michael Bette; Jürgen Adamkiewicz; Sabine Müller-Brüsselbach; Rolf Müller; Jochen A. Werner; Robert Mandic

Book ID
113833205
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
834 KB
Volume
45
Category
Article
ISSN
1368-8375

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## Abstract ## BACKGROUND: Tumor metabolism is an essential contributor to disease progression and response to treatment. An understanding of the metabolic phenotype of head and neck squamous cell carcinoma (HNSCC) will allow the development of appropriate antimetabolic strategies for this tumor t