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Annexin A2 localizes to the basal epithelial layer and is down-regulated in dysplasia and head and neck squamous cell carcinoma

✍ Scribed by Emma Pena-Alonso; Juan Pablo Rodrigo; Iñigo Casafont Parra; Juana Maria Garcia Pedrero; Maria Victoria Gonzalez Meana; Carlos Suarez Nieto; Manuel F. Fresno; Reginald O. Morgan; M. Pilar Fernandez


Book ID
116334637
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
849 KB
Volume
263
Category
Article
ISSN
0304-3835

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## Abstract It has been previously demonstrated that human carcinomas express interleukin‐2 receptor (IL‐2R) α, β, and γ chains. The β and γ chains of IL‐2R have intermediate binding affinity for IL‐2 and are responsible for the intracellular signaling cascades after IL‐2 stimulation. IL‐2Rα lacks