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Mutation in the β2m gene is not a frequent event in head and neck squamous cell carcinomas

✍ Scribed by Manita Feenstra; Erik Rozemuller; Karen Duran; Ilonka Stuy; Jan van den Tweel; Pieter Slootweg; Roel de Weger; Marcel Tilanus


Book ID
117415856
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
768 KB
Volume
60
Category
Article
ISSN
0198-8859

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Mutational analysis of the PTEN gene in
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## Loss of heterozygosity (LOH ) at chromosome band 10q23 occurs frequently in a wide variety of human tumors. A recently identified candidate tumor suppressor gene, PTEN located on 10q23, is mutated in multiple advanced cancers. To explore whether PTEN is associated with human squamous cell carci