The roles of cyclic nucleotide phosphodiesterases (PDEs) in steroidogenesis
β Scribed by Li-Chun Lisa Tsai; Joseph A Beavo
- Book ID
- 116383991
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 613 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1471-4892
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π SIMILAR VOLUMES
Phosphodiesterases (PDEs) are key enzymes involved in the regulation of intracellular cyclic nucleotide metabolism. The aim of the present study was to identify and to characterize the PDE isoenzymes present in the human detrusor smooth muscle. Human detrusor PDE isoenzymes were separated by Q-Sepha
Phosphodiesterases (PDEs) regulate intracellular cyclic nucleotide metabolism and, thus, contraction and relaxation of smooth musculature. The aim of the present study was to evaluate the functional effects of isoenzyme-selective inhibitors and their effects on cyclic nucleotide levels in the human