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PDE3 cyclic nucleotide phosphodiesterases and the compartmentation of cyclic nucleotide-mediated signalling in cardiac myocytes

✍ Scribed by Matthew A. Movsesian


Publisher
Springer
Year
2002
Tongue
English
Weight
151 KB
Volume
97
Category
Article
ISSN
0300-8428

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## Abstract The 46 kD isoform of the 2β€²3′‐cyclic nucleotide 3′‐phosphodiesterase (CNPi) was expressed in HeLa cells by transfection of its cDNA clone. The distribution of this polypeptide as mapped by indirect immunofluorescence and conventional epifluorescence microscopy appeared diffuse and gener