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The role of yeast artificial chromosome clones in generating genome maps

✍ Scribed by Burke, David T.


Book ID
122767694
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
756 KB
Volume
1
Category
Article
ISSN
0959-437X

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Genome mapping by arbitrary amplificatio
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Several methods have been described for using the polymerase chain reaction (PCR) to isolate fragments of DNA for genome mapping. We have developed an approach for isolating discrete fragments by amplifying DNA with single oligonucleotides (10mers) with arbitrarily selected sequences. The method is