The role of thrombospondin-1 in tumor pr
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George P. Tuszynski; Roberto F. Nicosia
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Article
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1996
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John Wiley and Sons
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English
β 834 KB
Thrombospondin (TSP-1) is a large glycoprotein secreted by platelets and synthesized by many cell types, including endothelial and tumor cells. Although controversy exists about the biological function of TSP-1, the following observations suggest that TSP-1 may potentiate tumor progression. (1) Tumo