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The role of upstream U3 sequences in HIV-1 replication and CD4+ T cell depletion in human lymphoid tissue ex vivo

✍ Scribed by Jan Münch; Devi Rajan; Elke Rücker; Steffen Wildum; Nadia Adam; Frank Kirchhoff


Book ID
113946492
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
431 KB
Volume
341
Category
Article
ISSN
0042-6822

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## Abstract Allogeneic immunity is one of the most potent natural immune responses. APOBEC3G (A3G) is an intracellular anti‐viral factor that deaminates cytidine to uridine. Allogeneic stimulation of human CD4^+^ T cells __in vitro__ upregulated A3G mRNA and a significant correlation was found betw