The role of transforming growth factor-β in suppression of hepatic metastasis from colon cancer
✍ Scribed by Chandrakanth Are; Neka Simms; Ashwani Rajupt; Michael Brattain
- Book ID
- 111221106
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 786 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1365-182X
No coin nor oath required. For personal study only.
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Transforming growth factor-s (TGFs) play a prominent role in tumour growth and metastasis by enhancing angiogenesis and suppressing immune surveillance. Despite the increased interest in the effect of TGFs on tumour progression, little is known about the importance of TGF3 and its receptor CD105
Transforming growth factor-b (TGF-b) plays a central role in a wide array of cellular functions including control of cell growth and differentiation, embryonic development, wound healing, angiogenesis, and immune regulation. In the gastrointestinal tract, TGF-b can either promote or suppress inflamm