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The role of the ubiquitin/proteasome system in cellular responses to radiation

✍ Scribed by McBride, William H; Iwamoto, Keisuke S; Syljuasen, Randi; Pervan, Milena; Pajonk, Frank


Book ID
110067769
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
297 KB
Volume
22
Category
Article
ISSN
0950-9232

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## Abstract The ubiquitin proteasome system is a potent regulatory mechanism used to control protein stability in numerous cellular processes, including neural development. Many neurodegenerative diseases are featured by the accumulation of UPS‐associated proteins, suggesting the UPS dysfunction ma