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The Role of the Tec Kinase Bruton's Tyrosine Kinase (Btk) in Leukocyte Recruitment

✍ Scribed by Block, Helena; Zarbock, Alexander


Book ID
111898592
Publisher
Informa plc
Year
2012
Tongue
English
Weight
424 KB
Volume
31
Category
Article
ISSN
0883-0185

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## Abstract Cytoplasmic protein‐tyrosine kinases (PTKs) are enzymes involved in transducing a vast number of signals in metazoans. The importance of the Tec family of kinases was immediately recognized when, in 1993, mutations in the gene encoding Bruton's tyrosine kinase (Btk) were reported to cau