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Model systems for analysing the function of Bruton's tyrosine kinase (Btk)

✍ Scribed by Paschalis Sideras; Anna Nilsson; Johan Forssell


Book ID
117326038
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
217 KB
Volume
35
Category
Article
ISSN
0161-5890

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Mutations of the human BTK gene coding f
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## X-linked agammaglobulinemia (XLA) is an immunodeficiency caused by mutations in the gene coding for Bruton agammaglobulinemia tyrosine kinase (BTK). A database (BTKbase ) of BTK mutations lists 544 mutation entries from 471 unrelated families showing 341 unique molecular events. In addition to