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The role of the support in solid phase peptide synthesis

โœ Scribed by Merrifield, Bruce


Publisher
Wiley (John Wiley & Sons)
Year
1984
Tongue
English
Weight
660 KB
Volume
16
Category
Article
ISSN
0007-1641

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๐Ÿ“œ SIMILAR VOLUMES


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Solid phase peptide synthesis a8 introduced by Merrifield' and modified by others2 is proving to be a valuable addition to the tools of the peptide chemist.

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A new aminoethyl-polystyrene linker, stable at low concentrations of TFA, has been developed for the solid phase synthesis of peptide amides. The described linker is stable under conditions which remove Bu(t) protecting groups (30-50% TFA in DCM) and the desired product can be finally cleaved off th