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The Role of the Pitx2c N-terminus in Left-Right Patterning

✍ Scribed by Annie Simard; Luciano Di Giorgio; Aimee K. Ryan


Book ID
116975819
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
55 KB
Volume
295
Category
Article
ISSN
0012-1606

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Role of asymmetric signals in left-right
✍ Hamada, Hiroshi ;Meno, Chikara ;Saijoh, Yukio ;Adachi, Hitoshi ;Yashiro, Kenta ; πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 87 KB πŸ‘ 2 views

LeftΒ±right asymmetric signaling molecules in mammals include three transforming growth factor b (TGFb)-related factors, Nodal, Lefty1 and Lefty2. They are all expressed on the left half of developing mouse embryos. Nodal acts as a left-side determinant by transducing signals through Smad and FAST an