New insights into left–right patterning: The role of pkd2 in the zebrafish
✍ Scribed by Jodi Schottenfeld; Rebecca D. Burdine
- Book ID
- 116975937
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 55 KB
- Volume
- 295
- Category
- Article
- ISSN
- 0012-1606
No coin nor oath required. For personal study only.
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Left±right asymmetric signaling molecules in mammals include three transforming growth factor b (TGFb)-related factors, Nodal, Lefty1 and Lefty2. They are all expressed on the left half of developing mouse embryos. Nodal acts as a left-side determinant by transducing signals through Smad and FAST an
## Abstract The body‐plan of vertebrates, while exteriorly essentially symmetric along its medio‐lateral plane, displays numerous left‐right differences in the disposition and placement of internal organs. Such left–right asymmetries, established during embryogenesis, are controlled by complex epig