✦ LIBER ✦

The role of the hepatitis B virus infection in patients with chronic hepatitis in argentina

✍ Scribed by Dr. Hugo Tanno; Oscar Fay; Jorge Findor; Estela Bruch Igartua; Robert J. Gerety; Mario Roncoroni; Girish N. Vyas

Publisher: John Wiley and Sons
Year: 1978
Tongue: English
Weight: 298 KB
Volume: 3
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890030205

No coin nor oath required. For personal study only.

✦ Synopsis

Over a seven-year period, we monitored 221 patients with chronic hepatitis from two medical centers. By using the counterlectrophoresis (CEP) test to detect the presence of HBsAg and anti-HBc, or both, we established that 87.7% of them had hepatitis B infection. Serum specimens originally found negative for HBsAg by CEP were further tested by reversed passive hemagglutination (RPH), and those originally found negative for anti-HBc by CEP were further tested by radioimmunoassay (RIA). Five patients were anti-HBc-positive and HBs-Ag-negative. No sex predominance was observed, but HBsAg incidence increased with increasing age. The HBeAg antigen was detected in 46.8% of the 161 cases tested for it; the most frequent subtype found was adw (63.7%). The present findings indicate that HBV infection largely contributes to the development of chronic hepatitis in Argentinian patients.

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