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The role of the CD44 cytoplasmic and transmembrane domains in constitutive and inducible hyaluronan binding

✍ Scribed by Jayne Lesley; Nicole English; Catherine Charles; Robert Hyman

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
157 KB
Volume
30
Category
Article
ISSN
0014-2980

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CD44 isoforms, such as CD44s (the standard form), contain at least one ankyrin-binding site within the 70-amino acid (aa) cytoplasmic domain and several hyaluronic acid (HA)-binding sites within the extracellular domain. To study the role of CD44s-ankyrin interaction in regulating human prostate tum