The role of the carbon skeleton of lysine in the biosynthesis of hemoglobin
โ Scribed by Kurt I. Altman; Leon L. Miller; Jonas E. Richmond
- Book ID
- 118839620
- Publisher
- Elsevier Science
- Year
- 1952
- Tongue
- English
- Weight
- 681 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0003-9861
No coin nor oath required. For personal study only.
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The Biosynthesis of Pramanicin: Origin of the Carbon Skeleton. -Incorporation of labeled acetates and serine into pramanicin (I) shows that its carbon skeleton is derived from eight acetate units and a serine residue, implying that the biosynthesis proceeds via an acyl-tetramic acid intermediate.
Extracts from Chlamydomonas, corn, soybean and tobacco were tested for enzymes of the lysine biosynthetic pathway. Dihydrodipicolinic acid (DHD) synthase, DHD reductase, diaminopimelate (DAP) epimerase and DAP decarboxylase were present in all. However, in contrast to the report ofWenko et al., meso