The Biosynthesis of Pramanicin: Origin of the Carbon Skeleton. -Incorporation of labeled acetates and serine into pramanicin (I) shows that its carbon skeleton is derived from eight acetate units and a serine residue, implying that the biosynthesis proceeds via an acyl-tetramic acid intermediate.
โฆ LIBER โฆ
The biosynthesis of sparsomycin. Elucidation of the origins of the carbon skeleton
โ Scribed by Parry, Ronald J.; Eudy, Mary Elizabeth.
- Book ID
- 126986626
- Publisher
- American Chemical Society
- Year
- 1988
- Tongue
- English
- Weight
- 332 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0002-7863
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\({ }^{13}\)-labeling experiments were performed to determine the simple precursor metabolites that contribute to the tetrapyrrole skeleton of heme \(\mathrm{d}_{1}\). By use of \(5-\left[4^{-13} \mathrm{C}\right]\) aminolevulinic acid it was determined that the skeleton is derived from \(8 \mathrm{