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The role of telomere dysfunction in driving genomic instability

✍ Scribed by Susan M. Bailey; Eli S. Williams; Robert L. Ullrich

Book ID
116539349
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
72 KB
Volume
1299
Category
Article
ISSN
0531-5131

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## Abstract The development of genomic instability is an important step toward generating the multiple genetic changes required for cancer. Telomere dysfunction is one of the factors that contribute to tumorigenesis. Telomeres shorten with each cell division in the absence of telomerase. Human mamm