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The role of synovial fibroblasts in pathologic bone resorption: RANKL and OPG expression by human and mouse fibroblasts in arthritis

✍ Scribed by Miklós Tunyogi-Csapó; Katalin Kis-Tóth; Csaba Vermes; Marianna Radács; Bálint Farkas; Tibor T. Glant; Tamás Illés

Book ID: 116320923
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 52 KB
Volume: 43
Category: Article
ISSN: 8756-3282
DOI: 10.1016/j.bone.2008.08.010

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## Abstract ## Objective To compare gene expression in normal and osteoarthritic (OA) human chondrocytes using microarray technology. Of the novel genes identified, we selected follistatin, a bone morphogenetic protein (BMP) antagonist, and investigated its expression/regulation as well as that of