๐”– Bobbio Scriptorium
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The Role of Sirtuins in the Control of Metabolic Homeostasis

โœ Scribed by Jiujiu Yu; Johan Auwerx


Book ID
111399351
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
239 KB
Volume
1173
Category
Article
ISSN
0890-6564

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The fasting-activated longevity protein sirtuin 1 (SirT1) promotes gluconeogenesis in part, by increasing transcription of the key gluconeogenic genes pepck1 and g6pase, through deacetylating PGC-1โฃ and FOXO1. In contrast, signal transducer and activator of transcription 3 (STAT3) inhibits glucose p