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The role of self-peptides in the development of CD4+ CD25+ regulatory T cells

✍ Scribed by Cristina Cozzo Picca; Andrew J Caton

Book ID
108099488
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
125 KB
Volume
17
Category
Article
ISSN
0952-7915

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## Abstract Although the phenotypic and regulatory properties of the CD4^+^CD25^+^ T cell lineage (Treg cells) have been well described, the specificities remain largely unknown. We demonstrate here that the CD4^+^CD25^+^ Treg population includes the recognition of a broad spectrum of human TCR CDR