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The role of Runx1 in the embryonic hematopoietic stem cell supportive microenvironment

✍ Scribed by Esther Haak; Claudia Orelio; Kirsty Harvey; Marian Peeters; Fredrik Wallberg; Rob Ploemacher; Elaine Dzierzak

Book ID
116304250
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
51 KB
Volume
38
Category
Article
ISSN
1079-9796

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## Abstract Lineage‐specific transcription factors must be precisely regulated during stem cell self‐renewal and lineage commitment decisions. The role of specific transcription factors in hematopoietic stem cell (HSC) fate decisions has derived largely from genetic strategies, primarily gene‐targe