The role of reductive enzymes in cancer cell resistance to mitomycin C
β Scribed by Jeffrey Cummings
- Book ID
- 117836160
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 140 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1368-7646
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π SIMILAR VOLUMES
This study was undertaken to elucidate the mechanism@) of cross-resistance to cisplatin (CDDP) in a mitomycin C (MMC)resistant human bladder cancer cell line, J82/MMC. The J82/ MMC cell line displayed 2-to 3-fold cross-resistance to CDDP and carboplatin when compared to the parental )82/WT cells. Dr
This study describes characteristics of a human bladder cancer cell line J82/MMC that is 6-fold more resistant to mitomycin C (MMC) than the parental cells. The J82/MMC subline was isolated by repeated continuous exposures of the J82/WT cells to increasing concentrations of MMC. The J82/MMC cell lin