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The role of recombination in the evolvement of the fragile X mutation

✍ Scribed by Tamar Schaap


Publisher
Springer
Year
1989
Tongue
English
Weight
321 KB
Volume
82
Category
Article
ISSN
0340-6717

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Three females were identified who have apparent reversal of fragile X premutations. Based on haplotype analysis of nearby markers, they were found to have inherited a fragile X chromosome from their premutation carrier mothers, and yet had normal size FMRl repeat alleles. The changes in repeat sizes