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Role of DNA methylation in X inactivation and the fragile X syndrome

✍ Scribed by Migeon, Barbara R.


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
180 KB
Volume
46
Category
Article
ISSN
0148-7299

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In the fragile X female carriers the degree of cognitive impairment appears to be correlated with activation status of the X chromosome bearing the expanded trinucleotide repeat in the promoter of the FMR1 gene. In this study we asked if the deviations from the primarily random pattern of X inactiva