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An assay for X inactivation based on differential methylation at the fragile X locus,FMR1

โœ Scribed by Carrel, Laura; Willard, Huntington F.


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
28 KB
Volume
64
Category
Article
ISSN
0148-7299

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Methylation ofHpaII site at the human DX
โœ Khalifa, M.M. ;Struthers, J.L. ;Maurice, S. ;Harrison, Kirk ;Duncan, A.M.V. ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 152 KB ๐Ÿ‘ 1 views

The highly polymorphic human DXS16 locus on Xp22 contains a BglII restriction fragment length polymorphism with 33% heterozygosity. We report that methylation of the HpaII site, 3.1 kb away from this restriction fragment length polymorphism, correlates with X-inactivation. The BglII polymorphism dis