The role of pyrophosphate/phosphate homeostasis in terminal differentiation and apoptosis of growth plate chondrocytes
โ Scribed by Hyon Jong Kim; John D. Delaney; Thorsten Kirsch
- Book ID
- 116323568
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 817 KB
- Volume
- 47
- Category
- Article
- ISSN
- 8756-3282
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The purpose of this study was to investigate the mechanism of cell death in chondrocytes of the growth plate. In the degenerative chondrocyte zone of the growth plate, apoptotic chondrocytes were defeated by the in situ nick end labelling method, by DNA analysis in agarose gel, and by electron micro
Endochondral bone formation involves the progression of epiphyseal growth plate chondrocytes through a sequence of developmental stages which include proliferation, differentiation, hypertrophy, and matrix calcification. To study this highly coordinated process, we infected growth plate chondrocytes