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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

โœ Scribed by Kawai, Taro; Akira, Shizuo

Book ID
109920862
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
779 KB
Volume
11
Category
Article
ISSN
1529-2908

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During infection or tissue damage, the innate immune system detects and responds to nucleic acids released from pathogens or damaged host cells. Accumulating evidence has showed that specific sequences, modifications or structures of nucleic acids influence their immunomodulatory activities. Resulti