The role of p53 protein family in gastrointestinal malignancies
โ Scribed by Zaika, A I; El-Rifai, W
- Book ID
- 110017197
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 87 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1350-9047
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
p53-mediated apoptosis involves multiple mechanisms. A number of p53-regulated apoptosis-related genes have been identified. Some of these genes encode proteins that are important in controlling the integrity of mitochondria while the others code for membrane death receptors. p53 may also induce apo
B cell lymphoma gene-2 (Bcl-2) is the prototypic member of a growing family of proteins that play evolutionarily conserved, key regulatory roles in apoptosis. The Bcl-2 family members are characterized by the presence of one or more Bcl-2 homology domains and are comprised of both the prosurvival an