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The role of oxidative stress in the ochratoxin A-mediated toxicity in proximal tubular cells

✍ Scribed by G.J Schaaf; S.M Nijmeijer; R.F.M Maas; P Roestenberg; E.M de Groene; J Fink-Gremmels


Book ID
117617940
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
403 KB
Volume
1588
Category
Article
ISSN
0925-4439

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## Abstract The aim of this study was to find out whether very low doses of nephrotoxic and hepatotoxic mycotoxins ochratoxin A (OTA) and fumonisin B~1~ (FB~1~) induce oxidative stress in rat kidney and liver and whether their effect is synergistic. Rats were treated orally with OTA (5 ng/kg b.w. a