The role of mycophenolate mofetil in the management of autoimmune hepatitis and overlap syndromes
β Scribed by A. M. C. Baven-Pronk; M. J. Coenraad; H. R. van Buuren; R. A. de Man; K. J. van Erpecum; M. M. H. Lamers; J. P. H. Drenth; A. P. van den Berg; U. H. Beuers; J. den Ouden; G. H. Koek; C. M. J. van Nieuwkerk; G. Bouma; J. T. Brouwer; B. van Hoek
- Book ID
- 108606346
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 345 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0269-2813
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Mycophenolate mofetil (MM) is the ester derivative of mycophenolic acid (MPA), which exerts immunosuppressive activity by inhibiting de novo purine biosynthesis. Following animal models and pilot studies in human renal allograft recipients that confirmed MM's ability to prevent and half rejection ep
## Abstract Mycophenolate mofetil 1.5 g daily (30 mg/kg body weight) was given to a patient with ankylosing spondylitis, ulcerative colitis, and severe refractory polymyositis after conventional treatment regimes had failed. No severe side effects occurred. Considerable improvement of clinical symp