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Mycophenolate mofetil in the therapy of polymyositis associated with a polyautoimmune syndrome

✍ Scribed by C. Schneider; R. Gold; M. Schäfers; K.V. Toyka


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
162 KB
Volume
25
Category
Article
ISSN
0148-639X

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✦ Synopsis


Abstract

Mycophenolate mofetil 1.5 g daily (30 mg/kg body weight) was given to a patient with ankylosing spondylitis, ulcerative colitis, and severe refractory polymyositis after conventional treatment regimes had failed. No severe side effects occurred. Considerable improvement of clinical symptoms and electromyographic findings were seen within 6 months after the initiation of mycophenolate mofetil, allowing for tapering and discontinuation of methylprednisolone. Mycophenolate mofetil may be considered as an useful alternative in the treatment of polymyositis when standard therapeutic regimens fail. © 2002 John Wiley & Sons, Inc. Muscle Nerve 25: 286–288, 2002 DOI 10.1002/mus.10026


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