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The role of muscle biopsy in analysis of the dystrophin gene in Duchenne muscular dystrophy: experience of a national referral centre

✍ Scribed by Sylvie Tuffery-Giraud; Céline Saquet; Sylvie Chambert; Bernard Echenne; Jean Marie Cuisset; François Rivier; Mireille Cossée; Christophe Philippe; Nicole Monnier; Eric Bieth; Dominique Recan; Marie Antoinette Voelckel; Serge Perelman; Jean-Claude Lambert; Sue Malcolm; Mireille Claustres


Book ID
116792201
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
223 KB
Volume
14
Category
Article
ISSN
0960-8966

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To compare the frequency and distribution of rearrangements in the dystrophin gene in Duchenne muscular dystrophy (DMD) between Japanese DMD patients and those in North America and Europe, Southern blot analyses of the dystrophin gene were carried out in 88 probands classified as DMD. Gene rearrange