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Transcription of the dystrophin gene in Duchenne muscular dystrophy muscle

โœ Scribed by Francesco Muntoni; Peter N. Strong


Book ID
115922050
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
384 KB
Volume
252
Category
Article
ISSN
0014-5793

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Alternative dystrophin gene transcripts
โœ Scott J. Schatzberg; Louise V.B. Anderson; Stephen D. Wilton; Joe N. Kornegay; C ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 355 KB

Golden retriever muscular dystrophy (GRMD), the canine model of Duchenne muscular dystrophy (DMD), is caused by a splice site mutation in the dystrophin gene. This mutation predicts a premature termination codon in exon 8 and a peptide that is 5% the size of normal dystrophin. Western blot analysis