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The role of membrane rafts in Lck transport, regulation and signalling in T-cells

✍ Scribed by Ventimiglia, Leandro N.; Alonso, Miguel A.

Book ID
121855622
Publisher
Portland Press
Year
2013
Tongue
English
Weight
888 KB
Volume
454
Category
Article
ISSN
0264-6021

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## Abstract Although signal pathways triggered __via__ the CD40 molecule are well characterized, those induced __via__ CD154 are less known. This study demonstrates that engagement of CD154 in Jurkat D1.1 cells with soluble CD40 leads to PKC α and δ activation, calcium mobilization, and phosphoryla