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The Role of Lipid Rafts in T Lymphocyte Signal Transduction with Aging

✍ Scribed by TAMAS FULOP JR.; NADINE DOUZIECH; ANIS LARBI; GILLES DUPUIS

Book ID: 111397751
Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 398 KB
Volume: 973
Category: Article
ISSN: 0890-6564
DOI: 10.1111/j.1749-6632.2002.tb04655.x

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## Abstract Although signal pathways triggered __via__ the CD40 molecule are well characterized, those induced __via__ CD154 are less known. This study demonstrates that engagement of CD154 in Jurkat D1.1 cells with soluble CD40 leads to PKC α and δ activation, calcium mobilization, and phosphoryla