The role of mass spectrometry in the analysis of vitamin D compounds
β Scribed by Rose M. Gathungu; Caroline C. Flarakos; G. Satyanarayana Reddy; Paul Vouros
- Book ID
- 115559926
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 535 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0277-7037
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Tandem mass spectrometry (MS/MS) has the significant advantage of improving selectivity and overcoming interferences present in conventional mass spectrometry. The quantitative use of MS/MS is discussed with reference to sources of instrumental error and ways to minimize such errors. Key parameters
The mass spectral fragmentation of p-nitrobenzoyl esters of vitamin D, stereoisomers has been investigated. The differences in the intensities of the main characteristic ions provide a basis for ( E )or (Z)-configurational assignments to the compounds of this series.