✦ LIBER ✦

The role of macrophages and immunocytes in the pathogenesis of pulmonary diseases due to mineral dusts

✍ Scribed by Benvenuto Pernis; Enrico C. Vigliani

Publisher: John Wiley and Sons
Year: 1982
Tongue: English
Weight: 343 KB
Volume: 3
Category: Article
ISSN: 0271-3586
DOI: 10.1002/ajim.4700030203

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

There is considerable evidence of generalized stimulation of the immune system in pulmonry dust diseases. This stimulation involves both the T‐ and the B‐arms of the immune system. A reasonable explanation of this immune stimulation resides in an effect of the mineral dusts on the macrophages. This effect is likely to be mediated by the production of interleukin‐1. Since the same substance also stimulates fibroblasts, a unified view of the pathogenesis of pulmonary dust diseases is now possible.

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