The recently identified Alzheimer's disease-associated presenilin 1 and 2 (PS1 and PS2) genes encode two homologous multi membrane-spanning proteins. Rabbit antibodies to the N-terminal domain of PS1 detected PS1 in human neuroblastoma SH-SY5Y wild type and PS1 transfectants (SY5Y-PS1) as well as in
β¦ LIBER β¦
Cell and molecular neurobiology of presenilins: A role for the endoplasmic reticulum in the pathogenesis of Alzheimer's disease?
β Scribed by Mark P. Mattson; Qing Guo
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 283 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0360-4012
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