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The role of lithocholic acid in the regulation of bile acid detoxication, synthesis, and transport proteins in rat and human intestine and liver slices

✍ Scribed by Ansar A. Khan; Edwin C.Y. Chow; Robert J. Porte; K. Sandy Pang; Geny M.M. Groothuis

Book ID
116920337
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
780 KB
Volume
25
Category
Article
ISSN
0887-2333

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Regulation of bile acid synthesis. II. E
Regulation of bile acid synthesis. II. Effect of bile acid feeding on enzymes regulating hepatic cholesterol and bile acid synthesis in the rat
✍ Douglas M. Heuman; Z. Reno Vlahcevic; Marsha L. Bailey; Phillip B. Hylemon πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 761 KB

Bile acid synthesis is believed to be regulated by bile salts returning to the liver via the portal vein and suppressing cholesterol 7a-hydroxylase, the rate-limiting enzyme in the bile acid biosynthesis pathway. In order to characterize the relative effectiveness of bile salts in regulating bile ac