The role of insulin-like growth factor II in the malignant transformation of rat liver oval cells
β Scribed by N Zhang; K Siegel; M Odenthal; R Becker; F Oesch; H P Dienes; P Schirmacher; P Steinberg
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 340 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
β¦ Synopsis
Abbreviations: IGF II, insulin-like growth factor II; IGF1R, type 1 insulin-like growth in which oval cell lines established from the livers of unfactor receptor; M6P/IGF2R, type 2 insulin-like growth factor receptor; FBS, fetal bovine treated 36 or carcinogen-treated rats [40] have been transserum; cDNA, complementary DNA; mRNA, messenger RNA; IgG, immunoglobulin G. formed in vitro and give rise to cholangiocellular as well as From the
π SIMILAR VOLUMES
Haemangiopericytoma is a rare soft tissue tumour originating from the contractile pericapillary cells. Relatively little is known about its molecular pathogenesis. To address this issue, the insulin-like growth factor family (IGFs) was analysed in 19 tumours collected from a human tumour bank networ
The ability of acute insulin treatment to elicit a redistribution of the liver insulin-like growth factor-II/ mannose 6-phosphate (IGF-II/M6P) receptor has been studied in rats, using cell fractionation. Injection of insulin (0.4 -50 g) led to a time-and dose-dependent decrease in IGF-II binding act
## Abstract Apart from hepatic stellate cells (HSC), liver myofibroblasts (MF) represent a second mesenchymal cell population involved in hepatic fibrogenesis. The IGF system including the insulinβlike growth factors I and II (IGFβI, βII), their receptors (IGFβI receptor, IGFβIR; IGFβII/mannose 6βp
NKR-P1 (3.2.3, IgG1) was raised and conjugated with fluorescein P1, natural killer receptor protein 1; mAbs, monoclonal antibodies; LU, lytic unit. isothiocyanate in our laboratory for the identification of NK cells.