✦ LIBER ✦

Role of the Ha-ras gene in the malignant transformation of rat liver oval cells

✍ Scribed by Pablo Steinberg; Heinz Frank; Margarete Odenthal; Hans-Peter Dienes; Albrecht Seidel

Publisher: John Wiley and Sons
Year: 1997
Tongue: French
Weight: 305 KB
Volume: 71
Category: Article
ISSN: 0020-7136
DOI: 10.1002/(sici)1097-0215(19970516)71:4<680::aid-ijc27>3.0.co;2-e

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Alterations in the glycolytic and glutam

Alterations in the glycolytic and glutaminolytic pathways after malignant transformation of rat liver oval cells

✍ Sybille Mazurek; Erich Eigenbrodt; Klaus Failing; Pablo Steinberg 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 215 KB 👁 1 views

The role of wild-type and mutated N-ras

The role of wild-type and mutated N-ras in the malignant transformation of liver cells

✍ Claudia Schleger; Rosario Heck; Pablo Steinberg 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 381 KB 👁 1 views

In order to determine the role of N-ras overexpression and mutation in malignant liver cell transformation, wild-type and mutated N-ras were transfected into the rat liver epithelial cell line OC/CDE 22, and N-ras expression, growth kinetics, growth in soft agar, and tumorigenicity in vivo as well a

Specific expression of the ras-Related r

Specific expression of the ras-Related rab3A gene in human normal and malignant neuroendocrine cells

✍ Stéphane Culine; Marie-Francoise Rousseau-Merck; Nicole Honoré; C. Nezelof; Birg 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 469 KB 👁 2 views

Regulation of cyclooxygenase gene expres

Regulation of cyclooxygenase gene expression in rat endometrial stromal cells: The role of epidermal growth factor

✍ Bany, Brent M. ;Kennedy, Thomas G. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 183 KB 👁 2 views

Epidermal growth factor stimulates prostaglandin production and cyclooxygenase activity in endometrial stromal cells isolated from the uteri of ovariectomized rats sensitized for the decidual reaction. The present study examined the effect of epidermal growth factor on cyclooxygenase-1 and cyclooxyg

Alterations in the Ha-ras-1 and the p53

Alterations in the Ha-ras-1 and the p53 pathway genes in the progression of N-methyl-N-nitrosourea–induced rat mammary tumors

✍ Katherine E. McKenzie; Barbara A. Armstrong; Ying Chen; Mahalakshmi Nagarajan; C 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 217 KB 👁 2 views

Well-differentiated mammary carcinomas carrying mutated Ha-ras-1 oncogenes arise frequently in pubescent rats exposed to the direct-acting methylating agent N-methyl-N-nitrosourea (MNU). When these tumors are serially transplanted, they acquire more aggressive phenotypes. To determine the genetic al

Modifications of the hepatocyte growth f

Modifications of the hepatocyte growth factor/c-met pathway by constitutive expression of transforming growth factor-α in rat liver epithelial cells

✍ Sharon C. Presnell; Donna B. Stolz; Wendy M. Mars; Minji Jo; George K. Michalopo 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 368 KB 👁 1 views

We have previously shown that rat liver epithelial cells (RLEC) transfected with and constitutively expressing transforming growth factor-α (TGF-α) have an enhanced mitogenic response to hepatocyte growth factor (HGF). In the study reported here, we examined tumor clones derived from the TGF-α trans